{"id":366,"date":"2012-11-28T15:32:41","date_gmt":"2012-11-28T07:32:41","guid":{"rendered":"http:\/\/www.hzaumycology.com\/chenlianfu_blog\/?p=366"},"modified":"2012-12-29T05:30:13","modified_gmt":"2012-12-28T21:30:13","slug":"cog%e5%88%86%e7%b1%bb","status":"publish","type":"post","link":"http:\/\/www.chenlianfu.com\/?p=366","title":{"rendered":"COG\u5206\u7c7b"},"content":{"rendered":"

\u672c\u6587\u8bb2\u8ff0\u5982\u4f55\u5bf9\u57fa\u56e0\u7ec4\u9884\u6d4b\u57fa\u56e0\u8fdb\u884cCOG\u5206\u7c7b\u3002<\/p>\n

\u4e00 COG\u7b80\u4ecb<\/h1>\n

COG\uff0c\u5373Clusters of Orthologous Groups of proteins\u3002<\/p>\n

\u5176\u7f51\u5740\u4e3b\u9875\u4e3a\uff1a http:\/\/www.ncbi.nlm.nih.gov\/COG\/\u3002<\/p>\n

\u7f51\u9875\u7248\u4f7f\u7528\u5de5\u5177\u7f51\u5740\uff1a http:\/\/www.ncbi.nlm.nih.gov\/COG\/old\/xognitor.html\u3002<\/p>\n

\u4f7f\u7528\u8bf4\u660e\u6587\u6863\u7f51\u5740\uff1a http:\/\/www.nlm.nih.gov\/COG\/old\/COGhelp.html\u3002<\/p>\n

\u5176FTP\u7ad9\u70b9\u4e3a: ftp:\/\/ftp.ncbi.nih.gov\/pub\/COG\/\u3002<\/p>\n

\u901a\u8fc7\u89c2\u770b\u5176\u4e3b\u9875\u548c\u8bf4\u660e\u6587\u6863\uff0c\u53ef\u4ee5\u7406\u89e3\u4e3aCOG\u662fNCBI\u7684\u6570\u636e\u5e93\u3002COG\u7684\u4e2d\u6587\u91ca\u4e49\u5373\u201c\u540c\u6e90\u86cb\u767d\u7c07\u201d\u3002COG\u5206\u4e3a\u4e24\u7c7b\uff0c\u4e00\u7c7b\u662f\u539f\u6838\u751f\u7269\u7684\uff0c\u53e6\u4e00\u7c7b\u662f\u771f\u6838\u751f\u7269\u3002\u539f\u6838\u751f\u7269\u7684\u4e00\u822c\u79f0\u4e3aCOG\u6570\u636e\u5e93\uff1b\u771f\u6838\u751f\u7269\u7684\u4e00\u822c\u79f0\u4e3aKOG\u6570\u636e\u5e93\u3002<\/p>\n

COG\u6ce8\u91ca\u4f5c\u7528\uff1a1. \u901a\u8fc7\u5df2\u77e5\u86cb\u767d\u5bf9\u672a\u77e5\u5e8f\u5217\u8fdb\u884c\u529f\u80fd\u6ce8\u91ca\uff1b 2. \u901a\u8fc7\u67e5\u770b\u6307\u5b9a\u7684COG\u7f16\u53f7\u5bf9\u5e94\u7684protein\u6570\u76ee\uff0c\u5b58\u5728\u53ca\u7f3a\u5931\uff0c\u4ece\u800c\u80fd\u63a8\u5bfc\u7279\u5b9a\u7684\u4ee3\u8c22\u9014\u5f84\u662f\u5426\u5b58\u5728\uff1b 3. \u6bcf\u4e2aCOG\u7f16\u53f7\u662f\u4e00\u7c7b\u86cb\u767d\uff0c\u5c06query\u5e8f\u5217\u548c\u6bd4\u5bf9\u4e0a\u7684COG\u7f16\u53f7\u7684proteins\u8fdb\u884c\u591a\u5e8f\u5217\u6bd4\u5bf9\uff0c\u80fd\u786e\u5b9a\u4fdd\u5b88\u4f4d\u70b9\uff0c\u5206\u6790\u5176\u8fdb\u5316\u5173\u7cfb\u3002<\/p>\n

\u4e8c \u5c06\u5e8f\u5217\u8fdb\u884cCOG\u5206\u7c7b\u7684\u6b65\u9aa4<\/h1>\n

1. COG\u7684ftp\u91cc\u8fb9\u63d0\u4f9b\u4e86\u4e00\u4e2a\u540d\u4e3amyva\u7684\u6587\u4ef6\uff0c\u8be5\u6587\u4ef6\u91cc\u9762\u4e3aCOG\u6570\u636e\u5e93\u7684\u86cb\u767d\u8d28\u5e8f\u5217\uff0c\u6709192987\u6761\u3002\u5c06\u8be5\u5e8f\u5217\u6587\u4ef6\u4f7f\u7528\u4f7f\u7528ncbi-blast-2.2.26+\u4e2d\u7684blastdb\u7a0b\u5e8f\u5236\u4f5c\u51fa\u4e00\u4e2a\u524d\u7f00\u4e3acog\u7684\u86cb\u767d\u8d28\u6570\u636e\u5e93\u3002<\/p>\n

2. \u5c06\u9700\u8981\u8fdb\u884cCOG\u6ce8\u91ca\u5e76\u5206\u7c7b\u7684DNA\u5e8f\u5217\u6216protein\u5e8f\u5217\u5206\u522b\u4f7f\u7528blastx\u6216blastp\u6bd4\u5bf9\u5230\u4e0a\u4e00\u6b65\u9aa4\u5efa\u597d\u7684cog\u6570\u636e\u5e93\u4e2d\u3002\u5f97\u51faxml\u7684\u6bd4\u5bf9\u7ed3\u679c\u3002<\/p>\n

3. \u6839\u636e\u4e0a\u4e00\u6b65\u9aa4\u7684\u6bd4\u5bf9\u7ed3\u679c\uff0c\u5f97\u51fa\u4e0equery\u5e8f\u5217\u76f8\u4f3c\u7684cog\u86cb\u767did\u3002\u5728COG\u7684ftp\u91cc\u9762\u6709\u4e00\u4e2a\u540d\u4e3awhog\u7684\u6587\u4ef6\uff0c\u8be5\u6587\u4ef6\u4e2d\u8bb0\u5f55\u7740COG\u6570\u636e\u4e2d\u7edd\u5927\u90e8\u5206\u7684\u86cb\u767d\u8d28id\u4ee5\u53ca\u5176\u6240\u5bf9\u5e94\u7684\u4ee5COG\u5f00\u5934\u7684protein\u7f16\u53f7\uff0c\u540c\u65f6\u4e5f\u8bb0\u5f55\u8fd9COG\u7f16\u53f7\u5bf9\u5e94\u7684\u529f\u80fd\u5206\u7c7b\u7f16\u53f7\u3002\u56e0\u6b64\uff0c\u53ef\u4ee5\u5f97\u51faquery\u5e8f\u5217\u6ce8\u91ca\u7684COG\u7f16\u53f7\u4ee5\u53ca\u5176\u529f\u80fd\u5206\u7c7b\u7f16\u53f7\u3002<\/p>\n

4. ftp\u4e2d\u8fd8\u6709\u4e00\u4e2a\u540d\u4e3afun.txt\u7684\u6587\u4ef6\uff0c\u8be5\u6587\u4ef6\u8bb0\u5f55\u8fd9COG\u7684\u529f\u80fd\u5206\u7c7b\u7f16\u53f7\uff0c\u53ca\u5176\u5bf9\u7f16\u53f7\u7684\u529f\u80fd\u63cf\u8ff0\u3002<\/p>\n

5. \u56e0\u6b64\uff0c\u6211\u7f16\u5199\u4e86\u4e00\u4e2a\u811a\u672c\u7a0b\u5e8f\u7528\u4e8eCOG\u5206\u7c7b\u6ce8\u91ca\u3002\u8be5\u811a\u672c\u7a0b\u5e8f\u540d\u5b57\u4e3acog.pl\u3002\u8f93\u5165\u4e3a\u6240\u9700\u8981\u8fdb\u884cCOG\u5206\u7c7b\u7684fasta\u5e8f\u5217\u6587\u4ef6\uff0c\u5f97\u51fa\u5e8f\u5217\u7684\u6bd4\u5bf9\u7ed3\u679c\u548c\u5206\u7c7b\u7edf\u8ba1\u3002<\/p>\n

\u4e09 \u5c06\u5e8f\u5217\u8fdb\u884cKOG\u5206\u7c7b<\/h1>\n

\u65b9\u6cd5\u548cCOG\u7684\u5206\u7c7b\u4e00\u81f4\u3002\u503c\u5f97\u6ce8\u610f\u7684\u662fKOG\u6570\u636e\u4e2dprotein\u7684\u7f16\u53f7\u662f\u4ee5LSE\u6216TWOG\u5f00\u5934\u7684\u3002\u540c\u6837\uff0c\u6211\u7f16\u5199\u4e86\u4e00\u4e2akog.pl\u3002<\/p>\n

\u56db \u8bf4\u660e\u8865\u5145<\/h1>\n

\u503c\u5f97\u8bf4\u660e\u7684\u662f\uff0cKOG\u6570\u636e\u5e93\u4e2d\u86cb\u767d\u8d28\u5e8f\u5217\u6570\u76ee\u4e3a112920\u6761\uff0c\u4f46\u662f\u5176\u4e2d\u6709protein\u7f16\u53f7\u7684\u53ea\u670927887\u6761\uff0c\u536025%\u3002\u800cCOG\u6570\u636e\u5e93\u4e2d\u86cb\u767d\u8d28\u5e8f\u5217\u6761\u6570\u4e3a192987\uff0c\u5176\u4e2d\u6709COG\u7f16\u53f7\u7684\u6709129326\u6761\uff0c\u536067%\u3002\u6240\u4ee5\u6bd4\u5bf9\u7ed3\u679c\u4e2d\uff0c\u5f88\u591a\u5e8f\u5217\u6bd4\u5bf9\u4e0a\u4e86KOG\u6570\u636e\u5e93\uff0c\u4f46\u662f\u6ca1\u6709protein\u7f16\u53f7\uff1b\u800c\u5728\u6bd4\u5bf9\u5230COG\u6570\u636e\u5e93\u65f6\u4f1a\u597d\u5f88\u591a\u3002<\/p>\n

\u6240\u4ee5\uff0c\u53ef\u4ee5\u5148\u5c06\u5e8f\u5217\u6bd4\u5bf9\u5230COG\u6570\u636e\u5e93\uff0c\u5f97\u51fa\u5206\u7c7b\u6570\u636e\uff1b\u7136\u540e\u5c06\u6ca1\u6709\u5206\u7c7b\u7f16\u53f7\u7684\u5e8f\u5217\u6311\u9009\u51fa\u6765\uff0c\u518d\u6bd4\u5bf9\u5230KOG\u6570\u636e\u5e93\uff0c\u5f97\u51fa\u5206\u7c7b\u6570\u636e\uff1b\u7136\u540e\u5c06\u4e24\u4e2a\u5206\u7c7b\u6570\u636e\u8fdb\u884c\u6574\u5408\uff0c\u7136\u540e\u753b\u51faCOG\u5206\u7c7b\u56fe\u3002<\/p>\n","protected":false},"excerpt":{"rendered":"

\u672c\u6587\u8bb2\u8ff0\u5982\u4f55\u5bf9\u57fa\u56e0\u7ec4\u9884\u6d4b\u57fa\u56e0\u8fdb\u884cCOG\u5206\u7c7b\u3002 \u4e00 COG\u7b80\u4ecb COG\uff0c\u5373Clus … \u7ee7\u7eed\u9605\u8bfb →<\/span><\/a><\/p>\n","protected":false},"author":1,"featured_media":0,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":[],"categories":[3],"tags":[23],"_links":{"self":[{"href":"http:\/\/www.chenlianfu.com\/index.php?rest_route=\/wp\/v2\/posts\/366"}],"collection":[{"href":"http:\/\/www.chenlianfu.com\/index.php?rest_route=\/wp\/v2\/posts"}],"about":[{"href":"http:\/\/www.chenlianfu.com\/index.php?rest_route=\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"http:\/\/www.chenlianfu.com\/index.php?rest_route=\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"http:\/\/www.chenlianfu.com\/index.php?rest_route=%2Fwp%2Fv2%2Fcomments&post=366"}],"version-history":[{"count":11,"href":"http:\/\/www.chenlianfu.com\/index.php?rest_route=\/wp\/v2\/posts\/366\/revisions"}],"predecessor-version":[{"id":421,"href":"http:\/\/www.chenlianfu.com\/index.php?rest_route=\/wp\/v2\/posts\/366\/revisions\/421"}],"wp:attachment":[{"href":"http:\/\/www.chenlianfu.com\/index.php?rest_route=%2Fwp%2Fv2%2Fmedia&parent=366"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"http:\/\/www.chenlianfu.com\/index.php?rest_route=%2Fwp%2Fv2%2Fcategories&post=366"},{"taxonomy":"post_tag","embeddable":true,"href":"http:\/\/www.chenlianfu.com\/index.php?rest_route=%2Fwp%2Fv2%2Ftags&post=366"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}