1. edgeR简介与安装

edgeR，Empirical analsis of digital gene expression data in R. Differential expression analysis of RNA-seq and digital gene expression profiles with biological replication. Uses empirical Bayes estimation and exact tests based on the negative binomial distribution. Also useful for differential signal analysis with other types of genome-scale count data.

To install this package, start R and enter:

    source("http://bioconductor.org/biocLite.R")
    biocLite("edgeR")

To cite this package in a publication, start R and enter:

    citation("edgeR")

To open the edgeR User’s Guide, start R and enter. edgeRUsersGuide.pdf will be downloaded.

    library(edgeR)
    edgeRUsersGuide()

2.